5× the concentration. Built for results, not promises.
Most serums settle for 1–2mg/mL. CUprene delivers 5mg/mL, formulated with Hyaluronic Acid and Niacinamide for real, measurable change.
GHK-Cu only works when your skin receives sufficient concentration. Most brands cut corners. CUprene doesn't. Our 0.5% formula at 5mg/mL is engineered to reach the dermis and activate the peptide pathways that drive real change, with Hyaluronic Acid and Niacinamide for a formula that performs as well as it feels.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Peer-Reviewed Research
Every ingredient in CUprene is backed by published, peer-reviewed research. No exceptions. Click any study to read what was actually found.
*These statements have not been evaluated by the FDA. Study summaries are provided for informational purposes. This product is not intended to diagnose, treat, cure, or prevent any disease.
The small tripeptide structure (Glycine-Histidine-Lysine) is compact enough to pass through the stratum corneum and reach live dermal cells.
GHK chelates copper (Cu²⁺) with high affinity, forming the active GHK-Cu complex that regulates gene expression related to skin repair.
The complex triggers expression of over 4,000 human genes involved in collagen synthesis, inflammation control, and antioxidant enzyme production.
With consistent use at clinical concentration, users report firmer texture, smoother tone, and measurably reduced wrinkle depth within weeks.
A naturally occurring tripeptide that declines with age. CUprene delivers it topically at a full 0.5% concentration, 5mg/mL, the highest available anywhere on the market.
GHK-Cu is paired with Hyaluronic Acid for a weightless texture that doesn't sacrifice depth. HA creates optimal conditions for peptide absorption while maintaining hydration that holds through the day.
Niacinamide (Vitamin B3) brightens uneven skin tone, minimizes the appearance of pores, and strengthens the skin barrier, working in perfect synergy with GHK-Cu to accelerate visible clarity and radiance alongside the peptide's repair activity.
pH-balanced to 5.5, matching skin's natural acid mantle, with a lightweight aqueous base that maximizes absorption without occluding pores or disrupting your skin barrier.
Start with a gentle, pH-balanced cleanser. Pat dry; damp skin actually improves absorption.
Fill the dropper to the 1mL line and dispense directly onto your face. Gently press and pat into skin. Do not rub.
Allow 60–90 seconds for full absorption before layering other products on top.
Seal with a moisturizer. Always finish your AM routine with broad-spectrum SPF 30+.